反应详情

The title compound was prepared by the method of Example 1 using 207 mg of 2-mercapto-5-methylbenzimidazole instead of 2-mercaptobenzimidazole and 260 mg of 2-(chloromethyl)-5,6-dimethylaniline hydrochloride instead of 2-(chloromethyl)-N,N-dimethylaniline in isopropyl alcohol. The basic extraction used 10% sodium hydroxide instead of sodium carbonate. The dichloromethane extract was dried over sodium sulfate, filtered, and concentrated in vacuo to 274 mg of the title compound as a gum. The compound was used in subsequent reactions without further purification.

1. extractionThe basic extraction
2. extractionThe dichloromethane extract
3. dry with materialwas dried over sodium sulfate
4. filtrationfiltered
5. concentrationconcentrated in vacuo to 274 mg of the title compound as a gum
6. customThe compound was used in subsequent reactions without further purification