3,5-Dichloroaniline → Benzamide

Participants

Reaction Steps

The title compound was synthesized in the same manner as Example 1 using 3,5-dichloroaniline (1.0 g, 6.2 mmol), CSI (0.64 mL, 4.4 mmol), and 3-amino-N-(3,4-difluoro-phenyl)-4-methoxy-benzamide (1.24 g, 7.0 mmol) to give 0.05 g of pure benzamide, 3-[[[[[(3,5-dichlorophenyl)amino]-carbonyl]amino]sulfonyl]amino]-N-(3,4-difluorophenyl)-4-methoxy-. Microanalysis: C21H16Cl2F2N4O5S; calculated: C=46.25; H=2.96; N=10.27; found: C=46.30; H=3.32; N=9.93. MS: M++1=544.9 Da.

Provenance & Evidence