3-Chloroaniline → Benzamide

Participants

Reaction Steps

The title compound was synthesized as in Example 1 using 3-chloroaniline (2.0 mL, 18.9 mmol), CSI (2.0 mL, 23.0 mmol), and 3-amino-N-(3,4difluoro-phenyl)-4-methoxy-benzamide (1.39 g, 5.0 mmol) to give 0.030 g of benzamide, 3-[[[[[(3-chlorophenyl)amino]carbonyl]amino]sulfonyl]amino]-N-(3,4-difluorophenyl)-4-methoxy-. Microanalysis: C21H17ClF2N4O5S; calculated: C=49.37; H=3.35; N=10.97. found: C=48.97; H=3.11; N=10.78. MS: M++1=511 Da. Mp 193-196° C.

Provenance & Evidence