Benzenamine, 3,5-bis(trifluoromethyl)- → Benzamide

Participants

Reaction Steps

The title compound was synthesized as in Example 1 using 3,5-bis(trifluoromethyl)aniline (1.3 mL, 8.2 mmol), CSI (0.85 mL, 9.8 mmol), and 3-amino-N-(3,4-difluorophenyl)-4-methoxy-benzamide (0.63 g, 2.3 mmol) to give 0.032 g of benzamide, 3-[[[[[[3,5-bis(trifluoromethyl)phenyl]amino]-carbonyl]amino]sulfonyl]amino]-N-(3,4-difluorophenyl)-4-methoxy-. Microanalysis: C23H16F8N4O5S.1.63 H2O; calculated: C=43.04; H=3.02; N=8.73. found: C=43.05; H=2.68; N=8.55. MS: M+−1=611 Da. Mp 175-178° C.

Provenance & Evidence