3-(Trifluoromethyl)aniline → Benzamide

Participants

Reaction Steps

The title compound was synthesized as in Example 1 using 3-trifluoromethylaniline (1.32 g, 10.6 mmol), CSI (0.85 mL, 9.8 mmol), and 3-amino-N-(3,4-difluoro-phenyl)-4-methoxy-benzamide (0.92 g, 3.3 mmol) to give 0.060 g of benzamide, N-(3,4-difluorophenyl)-4-methoxy-3-[[[[[[3-(trifluoromethyl)phenyl]amino]carbonyl]amino]sulfonyl]amino]-. Microanalysis: C22H17F5N4O5S; calculated: C=48.53; H=3.15; N=10.29. found: C=48.52; H=3.09; N=10.18. MS: M++1=545 Da. Mp 198-200° C.

Provenance & Evidence