HCID 22393753, compound → HCID 22393725, compound

Participants

Reaction Steps

Ethyl 1-benzyl-4-[2-(4-fluorophenoxy)ethyl)-2-piperazinecarboxylate (977 mg) synthesized in accordance with Example 241 described later was dissolved in ethanol (15 ml), and 210 mg of 10% Pd-C was added. After replacing the atmosphere with hydrogen, the mixture was stirred. After completion of the reaction, the solution was evaporated, to give 752 mg (100%) of the title compound as a crude product.

Provenance & Evidence