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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1071661Generated: November 4, 2026

α-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrile → 1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-fluoromethyl-2-pyridyloxy)ethyl]piperazine

https://huagongshe.com/reaction/1071661

Reaction equation

Participants

RoleNameHCIDCharge
Reactantα-(3-Iodopropyl)-α-(1-methylethyl)-2-thiopheneacetonitrileHCID 22393563—
ReactantHCID 22393784HCID 22393784—
Product1-[4-Cyano-4-(2-thienyl)-5-methylhexyl]-4-[2-(6-fluoromethyl-2-pyridyloxy)ethyl]piperazineHCID 22393630—

Reaction Steps

The title compound was synthesized in accordance with Example 75 from 4-cyano-4-(2-thienyl)-5-methylhexyl iodide and 1-[2-(6-fluoromethyl-2-pyridyloxy)ethyl]piperazine. The physico-chemical data of the compound was as below.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06906072B1
Source datasetuspto-grants-2005_06
ORD IDord-048f54def6fe4896ac58c0a05945aa87
Source noteuspto-grants-2005_06