Dichloromethane → (4-Amino-3-chlorophenyl)(piperazin-1-yl)methanone

HRID 107194Notes

Reaction equation

HRID 107194 reaction equation
[Cl:31][CH2:32][Cl:33].[F:24][C:25]([F:26])([F:27])[C:28]([OH:29])=[O:30].[NH2:1][c:2]1[c:3]([Cl:23])[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][N:11]([C:14]([O:15][C:16]([CH3:17])([CH3:18])[CH3:19])=[O:20])[CH2:12][CH2:13]2)[cH:21][cH:22]1>>[NH2:1][c:2]1[c:3]([Cl:23])[cH:4][c:5]([C:6](=[O:7])[N:8]2[CH2:9][CH2:10][NH:11][CH2:12][CH2:13]2)[cH:21][cH:22]1

Participants

4

Reactant 3

HCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 67059646HCID 67059646, compound

Product 1

HCID 64322197(4-Amino-3-chlorophenyl)(piperazin-1-yl)methanone

Sources & evidence

ORD record
ord-ab62da229ac046aca6b1e63e960bf84b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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