4-Pyridinecarboxaldehyde → HCID 22390208, compound

HRID 1072325Notes

Reaction equation

HRID 1072325 reaction equation
I[C:2]1[N:3]=[CH:4][N:5]2[CH:9]=[CH:8][S:7][C:6]=12.[N:10]1[CH:15]=[CH:14][C:13]([CH:16]=[O:17])=[CH:12][CH:11]=1>>[N:10]1[CH:15]=[CH:14][C:13]([CH:16]([OH:17])[C:2]2[N:3]=[CH:4][N:5]3[CH:9]=[CH:8][S:7][C:6]=23)=[CH:12][CH:11]=1

Participants

3

Reactant 2

HCID 133894-PyridinecarboxaldehydeHCID 177737777-Iodoimidazo[5,1-B]thiazole

Product 1

HCID 22390208HCID 22390208, compound

Procedure

7-[(Pyridin-4-yl)hydroxymethyl]imidazo[5,1-b]-thiazole (1.32 g) was prepared in the same manner as in step a) of Synthesis Example 1, except that 2.50 g of 7-iodoimidazo[5,1-b]thiazole and 1.05 ml of pyridine-4-aldehyde were used as the starting compounds.

Workup

  1. customof Synthesis Example 1

Sources & evidence

ORD record
ord-27b615139a98474fba8944f485a16105
Source dataset
uspto-grants-2005_06
Patent number
US06908913B2

Reaction notes

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