HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Bromophenacyl bromide → 1-(4-Bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Bromophenacyl bromide | HCID 7454 | — |
| Reactant | Benzenemethanamine, 2,4-dichloro-N-methyl- | HCID 485424 | — |
| Product | 1-(4-Bromophenyl)-2-((2,4-dichlorobenzyl)(methyl)amino)ethanone | HCID 22386828 | 69% |
Reaction Steps
(2,4-Dichloro-benzyl)-methyl-amine (see example 1, intermediate 1) and 2-bromo-1-(4-bromo-phenyl)-ethanone was reacted in analogy to the method described in example 1, intermediate 3. After analogous workup and chromatography on silica gel, the alkylation product was isolated in a yield of 69%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06911453B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-cd5a889ac9fd4955a4c6abb498a7a24c |
| Source note | uspto-grants-2005_06 |