Methylamine → [(4-Methanesulfonylphenyl)methyl](methyl)amine

HRID 1072515Notes

Reaction equation

Br[CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH3:12])(=[O:11])=[O:10])=[CH:5][CH:4]=1.[CH3:13][NH2:14]>>[CH3:12][S:9]([C:6]1[CH:7]=[CH:8][C:3]([CH2:2][NH:14][CH3:13])=[CH:4][CH:5]=1)(=[O:11])=[O:10]

Participants

Reactant 2

HCID 6329Methylamine

HCID 27335814-(Methylsulfonyl)benzyl Bromide

Product 1

HCID 22386825[(4-Methanesulfonylphenyl)methyl](methyl)amine

Procedure

(4-Methanesulfonyl-benzyl)-methyl-amine was synthesized starting from 1-bromomethyl-4-methanesulfonylbenzene and methylamine in a manner known to the skilled worker.

Sources & evidence

ORD record: ord-9747f8e039294d28b6fe2fa970f1651d
Source dataset: uspto-grants-2005_06
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06911453B2

Reaction notes

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