HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydroxide ethanol → Sodium (2R)-2-([4-[1-(4-pentylphenyl)-5-methyl-1H-pyrrol-2-yl]phenyl]oxy)-3-phenylpropanoate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydroxide ethanol | HCID 23692425 | — |
| Reactant | HCID 69732826 | HCID 69732826 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Sodium (2R)-2-([4-[1-(4-pentylphenyl)-5-methyl-1H-pyrrol-2-yl]phenyl]oxy)-3-phenylpropanoate | HCID 86759773 | 71% |
Reaction Steps
To a solution of (2R)-2-([4-[1-(4-pentylphenyl)-5-methyl-1H-pyrrol-2-yl]phenyl]oxy)-3-phenylpropanoic acid (621 mg, 1.33 mmol) in ethanol (10 ml) was added 1N sodium hydroxide-ethanol solution (1.3 ml, 1.3 mmol) and the mixture was concentrated. To the residue was added hexane to give the object compound as a solid. 460 mg, (yield: 71%)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06911468B2 |
| Source dataset | uspto-grants-2005_06 |
| ORD ID | ord-9f8437ac6a1f44b0a51a2320f2687028 |
| Source note | uspto-grants-2005_06 |