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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1072727Generated: November 3, 2026

Sodium hydroxide ethanol → Sodium (2R)-2-([4-[1-(4-pentylphenyl)-5-methyl-1H-pyrrol-2-yl]phenyl]oxy)-3-phenylpropanoate

https://huagongshe.com/reaction/1072727

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium hydroxide ethanolHCID 23692425—
ReactantHCID 69732826HCID 69732826—
SolventEthanolHCID 702—
ProductSodium (2R)-2-([4-[1-(4-pentylphenyl)-5-methyl-1H-pyrrol-2-yl]phenyl]oxy)-3-phenylpropanoateHCID 8675977371%

Reaction Steps

To a solution of (2R)-2-([4-[1-(4-pentylphenyl)-5-methyl-1H-pyrrol-2-yl]phenyl]oxy)-3-phenylpropanoic acid (621 mg, 1.33 mmol) in ethanol (10 ml) was added 1N sodium hydroxide-ethanol solution (1.3 ml, 1.3 mmol) and the mixture was concentrated. To the residue was added hexane to give the object compound as a solid. 460 mg, (yield: 71%)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06911468B2
Source datasetuspto-grants-2005_06
ORD IDord-9f8437ac6a1f44b0a51a2320f2687028
Source noteuspto-grants-2005_06