Hydrochloric Acid → HCID 22388387, compound

HRID 1072862Notes

Reaction equation

HRID 1072862 reaction equation
[C:1]([N:4]([CH2:17][C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=1[Cl:25])[C:5]1[CH:10]=[C:9]([C:11](=[O:13])[NH2:12])[CH:8]=[CH:7][C:6]=1[C:14](=[O:16])[NH2:15])(=O)[CH3:2].Cl>CO>[C:11]([C:9]1[CH:10]=[C:5]2[C:6]([C:14](=[O:16])[N:15]=[C:1]([CH3:2])[N:4]2[CH2:17][C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][C:19]=2[Cl:25])=[CH:7][CH:8]=1)(=[O:13])[NH2:12]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 22388498HCID 22388498, compound

Product 1

HCID 22388387HCID 22388387, compoundYield 102.2%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

2-((N-Acetyl)-(2,4-dichlorobenzyl)amino)-1,4-dicarbamoylbenzene (1.50 g) in a mixture of concentrated hydrochloric acid (10 ml) and methanol (30 ml) was heated under reflux for 30 min. After concentration, the object compound (1.46 g) was obtained as white crystals.

Workup

  1. temperaturewas heated
  2. temperatureunder reflux for 30 min
  3. concentrationAfter concentration

Sources & evidence

ORD record
ord-be1bc7f693774e5d94d69a32169f13d7
Source dataset
uspto-grants-2005_06
Patent number
US06911469B2

Reaction notes

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