Benzyl carbamate → 2-(((Benzyloxy)carbonyl)amino)-2-hydroxyacetic acid

Beteiligte Stoffe

Reaktionsschritte

Glyoxylic acid monohydrate (20.3 g, 221 mmol) and benzyl carbamate (30.6 g, 202 mmol) are added to ether (200 mL). The solution is allowed to stir for 24 h at rt. The resulting thick precipitate is filtered, and the residue is washed with ether, affording ([(benzyloxy)carbonyl]amino)(hydroxy)acetic acid (C150) as a white solid (47% yield). MS (CI) for C10H11NO5+H m/z: 226 (M+H).

Herkunft & Nachweise