Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Dimethylazanium;chloride | HCID 12954980 | — |
| Reactant | 10-(2-Aminoethyl)-8,9-dihydropyrido[1,2-a]indol-6(7H)-one | HCID 20030094 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | HCID 22158345 | HCID 22158345 | — |
Reaction Steps
8.9 g (0.022 mole) D4, 3.2 g (0.44 mole) dimethylammonium chloride and 6 g triethylamine were dissolved in 150 ml N,N-dimethylformamide and heated for 6 h at 90° C. The solvent was evaporated in vacuo and the residue extracted with 100 ml chloroform and 100 ml water. The organic layer was separated and dried. The solvent was evaporated and the residue crystallised from ethyl acetate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US04968699 |
|---|
| Source dataset | uspto-grants-1990_11 |
|---|
| ORD ID | ord-49d31f61ca904a36a14db9bf918bcf9b |
|---|
| Source note | uspto-grants-1990_11 |
|---|
