Dichloromethane → 2-Amino-3-[4-[2-amino-6-[1-[2-(6-cyano-3-pyridinyl)phenyl]-2,2,2-trifluoroethoxy]pyrimidin-4-yl]phenyl]propanoic acid
Reaction equation
[Cl:54][CH2:55][Cl:56].[F:47][C:48]([F:49])([F:50])[C:51]([OH:52])=[O:53].[NH2:1][c:2]1[n:3][c:4]([O:27][CH:28]([C:29]([F:30])([F:31])[F:32])[c:33]2[c:34](-[c:39]3[cH:40][n:41][c:42]([C:45]#[N:46])[cH:43][cH:44]3)[cH:35][cH:36][cH:37][cH:38]2)[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][CH:15]([C:16](=[O:17])[OH:18])[NH:19][C:20]([O:21][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:26])[cH:12][cH:13]2)[n:7]1>>[NH2:1][c:2]1[n:3][c:4]([O:27][CH:28]([C:29]([F:30])([F:31])[F:32])[c:33]2[c:34](-[c:39]3[cH:40][n:41][c:42]([C:45]#[N:46])[cH:43][cH:44]3)[cH:35][cH:36][cH:37][cH:38]2)[cH:5][c:6](-[c:8]2[cH:9][cH:10][c:11]([CH2:14][CH:15]([C:16](=[O:17])[OH:18])[NH2:19])[cH:12][cH:13]2)[n:7]1Participants
4
Reactant 3
Product 1
Sources & evidence
- ORD record
- ord-9f167458e8564c70821d0abd99fac459
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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