Sodium borohydride → HCID 22158384, compound

HRID 1073214Notes

Reaction equation

HRID 1073214 reaction equation
[CH:1]([C:3]1[N:10]2[C:6]([S:7][C:8]3[CH:14]=[CH:13][CH:12]=[CH:11][C:9]=32)=[N:5][C:4]=1[CH2:15][CH3:16])=[O:2].[BH4-].[Na+]>CO>[CH2:15]([C:4]1[N:5]=[C:6]2[N:10]([C:3]=1[CH2:1][OH:2])[C:9]1[CH:11]=[CH:12][CH:13]=[CH:14][C:8]=1[S:7]2)[CH3:16]

Participants

4

Reactant 2

HCID 4311764Sodium borohydrideHCID 22158396HCID 22158396, compound

Product 1

HCID 22158384HCID 22158384, compoundYield 63.4%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Furthermore, 3.88 g of 3-formyl-2-ethylimidazo[2,1-b]benzothiazole was suspended in 30 ml of methanol and 1.0 g of sodium borohydride was added to the suspension followed by refluxing for one hour. After completion of the reaction, the reaction solution was evaporated to dryness and the residue was washed with water. The crystals obtained were recrystallized from ethanol to give 2.48 g of the title compound.

Workup

  1. temperatureby refluxing for one hour
  2. customAfter completion of the reaction
  3. customthe reaction solution was evaporated to dryness
  4. washthe residue was washed with water
  5. customThe crystals obtained
  6. customwere recrystallized from ethanol

Sources & evidence

ORD record
ord-96418546548d42a68d0f07f4f2f8d39d
Source dataset
uspto-grants-1990_11
Patent number
US04968708

Reaction notes

Loading…