反应详情

To a solution of 2-(3-propyloxyphenyl)ethylamine prepared in a manner analogous to that described in Example 1E (2.69 g) in acetonitrile (40 cm3) was added triethylamine (3 cm3). A solution of 2-chlorocinnamoyl chloride (3.6 g) in acetonitrile (20 cm3) was added slowly, the reaction mixture being cooled in an ice bath. When addition was complete, the mixture was stirred at room temperature for 40 minutes, treated with water (60 cm3) and SVM (2 cm3) and stirred well. The resulting precipitate was filtered off, washed and air-dried (5.49 g) m.p. 96°-99° C.

1. temperaturethe reaction mixture being cooled in an ice bath
2. additionWhen addition
3. stirringstirred well
4. filtrationThe resulting precipitate was filtered off
5. washwashed
6. customair-dried (5.49 g) m.p. 96°-99° C.