反应详情

A solution of 6.45 g of 5-triflouromethylisatin in water was reacted with 7.97 g of 2-amino-1-(2'-fluoro[1,1'-biphenyl]-4-yl)-ethanone hydrochloride (example 17) by the procedure described in example 18, giving 9.0 g of the desired compound as a yellow solid, mp 255°-260° C.