Water → HCID 15085972, compound

HRID 1073275Notes

Reaction equation

HRID 1073275 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=[O:11])[C:5]2=O.Cl.[NH2:14][CH2:15][C:16]([C:18]1[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=1)=O.[OH2:25]>>[NH2:14][C:15]1[C:16]([C:18]2[CH:23]=[CH:22][C:21]([Cl:24])=[CH:20][CH:19]=2)=[N:7][C:8]2[C:4]([C:5]=1[C:6]([OH:11])=[O:25])=[CH:3][C:2]([Cl:1])=[CH:10][CH:9]=2

Participants

4

Reactant 3

HCID 962WaterHCID 872035-chloro-1H-indole-2,3-dioneHCID 27982112-Amino-1-(4-chlorophenyl)ethan-1-one hydrochloride

Product 1

HCID 15085972HCID 15085972, compound

Procedure

A solution of 4.54 g of 5-chloroisatin in water was reacted with 6.8 g of 2-amino-1-(4-chlorophenyl)ethanone hydrochloride by the procedure described in example 33, giving 6.27 g of the desired compound as a yellow solid,mp 240°-241° C.

Sources & evidence

ORD record
ord-77c117e2d8b644b6a37ff3942f8755c3
Source dataset
uspto-grants-1990_11
Patent number
US04968702

Reaction notes

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