Dideoxyadenosine → HCID 178520964, compound

HRID 1073492Notes

Reaction equation

HRID 1073492 reaction equation
C(O)C(N)(CO)C[OH:4].Cl.[C@@H:10]1([N:17]2[C:26]3[N:25]=[CH:24][N:23]=[C:21](N)[C:20]=3[N:19]=[CH:18]2)[O:16][C@H:13]([CH2:14][OH:15])[CH2:12][CH2:11]1>>[C@@H:10]1([N:17]2[C:26]3[N:25]=[CH:24][N:23]=[C:21]([OH:4])[C:20]=3[N:19]=[CH:18]2)[O:16][C@H:13]([CH2:14][OH:15])[CH2:12][CH2:11]1

Participants

3

Reactant 2

HCID 20039DideoxyadenosineHCID 93573Tromethamine hydrochloride

Product 1

HCID 178520964HCID 178520964, compound

Procedure

The washed cells described above were added to 0.05M Tris-HCl buffer (pH 7.2) containing 1 g/dl of 2',3'-dideoxyadenosine in a concentration of 5 g/dl followed by reacting at 30° C. for 2 hours. The amount of 2',3'-dideoxyinosine produced at this stage is shown in Table 2.

Sources & evidence

ORD record
ord-3b5689c101c944e2a1db21f8f4249fcf
Source dataset
uspto-grants-1990_11
Patent number
US04970148

Reaction notes

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