Isopropanol → HCID 178423755, compound

HRID 1073908Notes

Reaction equation

[NH2:1][C:2]1[N:7]=[C:6]([CH:8]2[C:13]3[CH:14]=[C:15]([C:18]#[N:19])[CH:16]=[CH:17][C:12]=3[O:11][C:10]([CH3:21])([CH3:20])[CH2:9]2)[CH:5]=[CH:4][CH:3]=1.C([OH:25])(C)C>>[NH2:1][C:2]1[CH:3]=[CH:4][CH:5]=[C:6]([CH:8]2[C:13]3[CH:14]=[C:15]([C:18]#[N:19])[CH:16]=[CH:17][C:12]=3[O:11][C:10]([CH3:21])([CH3:20])[CH2:9]2)[N+:7]=1[O-:25]

Participants

Reactant 2

HCID 3776Isopropanol

HCID 19895675HCID 19895675, compound

Product 1

HCID 178423755HCID 178423755, compound

Procedure

In an analogous manner to that described in the first paragraph of Example 7, from 4-(6-amino-2-pyridyl)-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-carbonitrile there was obtained 2-amino-6-(6-cyano-3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-4-yl)pyridine N-oxide of melting point 210°-212° C. (from isopropanol).

Sources & evidence

ORD record: ord-4789c4aa08c7438ca9adf9f4393928c1
Source dataset: uspto-grants-1990_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04971982

Reaction notes

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