反应详情

The procedure is as in Example 2 for the preparation of diethyl 2-dimethylamino-5-phenylthio-2,4-hexadienedioate, starting with N-(3-dimethylamino-3-ethoxycarbonylpropenylidene)-N-methylmethanaminium tetrafluoroborate (10 g), a 2M ethanolic solution of sodium ethylate (21 cc) and ethyl (3-methylbenzylthio)acetate (7.9 g) in ethanol (100 cc). Diethyl 2-dimethylamino-5-(3-methylbenzylthio)-2,4-hexadienedioate (11 g) is obtained in the form of a brown oil, and is used in the crude state in the subsequent syntheses.