Diisopropyl Ether → Lithium 4,5-dichloro-6-formyl-1,3-benzodioxole-2-carboxylate

HRID 1074190노트

반응식

HRID 1074190 반응식
O.[OH-].[Li+:3].[Cl:4][C:5]1[C:13]2[O:12][CH:11]([C:14]([O:16]CC)=[O:15])[O:10][C:9]=2[CH:8]=[C:7]([CH:19]=[O:20])[C:6]=1[Cl:21].C(OC(C)C)(C)C>CO>[Cl:4][C:5]1[C:13]2[O:12][CH:11]([C:14]([O-:16])=[O:15])[O:10][C:9]=2[CH:8]=[C:7]([CH:19]=[O:20])[C:6]=1[Cl:21].[Li+:3]

참가 물질

5

반응물 3

HCID 7914Diisopropyl EtherHCID 168937Lithium hydroxide, monohydrateHCID 14748638Ethyl 4,5-dichloro-6-formyl-1,3-benzodioxole-2-carboxylate

생성물 1

HCID 23683076Lithium 4,5-dichloro-6-formyl-1,3-benzodioxole-2-carboxylate수율 100.2%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

1.03 g of lithium hydroxide monohydrate are added to a solution of 7.0 g of ethyl 4,5-dichloro-6-formyl-1,3-benzodioxole-2-carboxylate in methanol under ice-cooling and the mixture is stirred at room temperature for 4 hours. Isopropyl ether is added to the reaction mixture and the resultant powdery materials are collected by filtration to give 6.48 g of lithium 4,5-dichloro-6-formyl-1,3-benzodioxole-2-carboxylate.

후처리

  1. temperaturecooling
  2. filtrationthe resultant powdery materials are collected by filtration

출처 및 근거

ORD 기록
ord-2b4ee162baf7426b8491bc40a08aabd3
출처 데이터셋
uspto-grants-1990_11
특허 번호
US04973600

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