Hydrochloric Acid → HCID 22155965, compound

HRID 1074201Notes

Reaction equation

HRID 1074201 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[N:12]([CH2:16][C:17]3[CH:22]=[CH:21][CH:20]=[CH:19][CH:18]=3)[CH:13]=[CH:14][N:15]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2].[ClH:23]>ClCCl.C(O)C>[ClH:23].[N+:1]([C:4]1[CH:9]=[CH:8][C:7]([S:10][C:11]2[N:12]([CH2:16][C:17]3[CH:18]=[CH:19][CH:20]=[CH:21][CH:22]=3)[CH:13]=[CH:14][N:15]=2)=[CH:6][CH:5]=1)([O-:3])=[O:2]

Participants

5

Reactant 2

HCID 313Hydrochloric AcidHCID 561240HCID 561240, compound

Product 1

HCID 22155965HCID 22155965, compound

Reagents, catalysts & solvents 2

HCID 702EthanolSolvent2×HCID 6344DichloromethaneSolvent

Procedure

The product from Example 28 was dissolved in mixture of dichloromethane and ethyl alcohol and treated with excess hydrogen chloride in ethyl alcohol. The solvents were removed in vacuo and the residue triturated with ether and filtered. The solid was recrystallized from methanol/ether to give the product as colorless prisms, mp 240°-245° C. (sealed tube).

Workup

  1. customThe solvents were removed in vacuo
  2. customthe residue triturated with ether
  3. filtrationfiltered
  4. customThe solid was recrystallized from methanol/ether
  5. customto give

Sources & evidence

ORD record
ord-560addb1ebed41a0b22d0de24f1d1697
Source dataset
uspto-grants-1990_11
Patent number
US04973599

Reaction notes

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