HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1074304Generated: October 26, 2026
Water → Methyl 4'-(benzyloxy)-[1,1'-biphenyl]-4-carboxylate
https://huagongshe.com/reaction/1074304
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Benzyl Bromide | HCID 7498 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 6-(1-Trifluoromethylheptyloxycarbonyl)-naphathalene-2-carboxylic acid chloride | HCID 14847573 | — |
| Solvent | N',N'-Dimethylformohydrazide | HCID 304376 | — |
| Product | Methyl 4'-(benzyloxy)-[1,1'-biphenyl]-4-carboxylate | HCID 15084903 | — |
Reaction Steps
The product obtained in Item (1) in the amount of 4.1 g was dissolved in 100 ml of dimethylaminoformamide. The solution was added with anhydrous potassium carbonate 3.6 g and after heating upto 110° C. dropped with benzyl bromide 4.1 g during one hour to be stirred thereafter at a temperature of 140° C. for 4 hours. The reaction solution was taken into a large amount of water to precipitate crystal, which was dried to obtain the captioned product in the amount of 6.6 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US04973738 |
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| Source dataset | uspto-grants-1990_11 |
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| ORD ID | ord-e5a603c947234c3a83f61e6dcab751dd |
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| Source note | uspto-grants-1990_11 |
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