反应详情

A mixture was prepared by adding 4.5 g of 6-chloro-7,8,9,10-tetrahydroimidazo[2,1-a]phthalazine to 8.7 g of pyrrolidine and this was heated at reflux for 6.5 hours during which time the mixture turned brown. The reaction mixture was then poured into about 150 ml of ice water. A solid formed immediately and this was separated by filtration and air dried to give 6-(1-pyrrolidinyl)-7,8,9,10-tetrahydroimidazo[2,1-a]phthalazine melting at about 128° C.

1. customA mixture was prepared
2. temperaturethis was heated
3. temperatureat reflux for 6.5 hours during which time the mixture
4. customA solid formed immediately
5. customthis was separated by filtration and air
6. customdried