反应详情

17.6 g 7-hydroxy-2-methyl-4H-1-benzopyrane-4-one-[J.Org. Chem. 24, 683, (1959)], 0.1 cm3 piperidine and 60 cm3 1-chloro-2,3-epoxy-propane were stirred for 9 hours at a temperature of 90° C. The mixture was worked up according to example 5 (b) and 19.0 g 1-chloro-3-(2-methyl-4H-1-benzopyrane-4-one-7-yloxy)-2-propanol was obtained (m.p. 104°-106° C.).