Epichlorohydrin → HCID 20496729, compound

HRID 1074458Notes

Reaction equation

HRID 1074458 reaction equation
[OH:1][C:2]1[CH:13]=[CH:12][C:5]2[C:6](=[O:11])[CH:7]=[C:8]([CH3:10])[O:9][C:4]=2[CH:3]=1.N1CCCCC1.[Cl:20][CH2:21][CH:22]1[O:24][CH2:23]1>>[Cl:20][CH2:21][CH:22]([OH:24])[CH2:23][O:1][C:2]1[CH:13]=[CH:12][C:5]2[C:6](=[O:11])[CH:7]=[C:8]([CH3:10])[O:9][C:4]=2[CH:3]=1

Participants

4

Reactant 3

HCID 7835EpichlorohydrinHCID 8082PiperidineHCID 53553097-hydroxy-2-methyl-4H-1-benzopyran-4-one

Product 1

HCID 20496729HCID 20496729, compound

Procedure

17.6 g 7-hydroxy-2-methyl-4H-1-benzopyrane-4-one-[J.Org. Chem. 24, 683, (1959)], 0.1 cm3 piperidine and 60 cm3 1-chloro-2,3-epoxy-propane were stirred for 9 hours at a temperature of 90° C. The mixture was worked up according to example 5 (b) and 19.0 g 1-chloro-3-(2-methyl-4H-1-benzopyrane-4-one-7-yloxy)-2-propanol was obtained (m.p. 104°-106° C.).

Sources & evidence

ORD record
ord-604bdc845e9d4e62b95833522e4ffdb6
Source dataset
uspto-grants-1983_07
Patent number
US04391821

Reaction notes

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