2-Phenylchroman-7-ol → 1-chloro-4-(2-phenyl-3,4-dihydro-2H-1-benzopyrane-7-yloxy)-2-butanol

Participants

Role	Name	HCID	Charge
Reactant	2-Phenylchroman-7-ol	HCID 3512638	—
Reactant	2-(2-Chloroethyl)oxirane	HCID 12519722	—
Reactant	1,4-Dichlorobutanol	HCID 19347542	—
Product	1-chloro-4-(2-phenyl-3,4-dihydro-2H-1-benzopyrane-7-yloxy)-2-butanol	HCID 20496726	—

Reaction Steps

The starting 1-chloro-4-(2-phenyl-3,4-dihydro-2H-1-benzopyrane-7-yloxy)-2-butanol was prepared from 2-phenyl-7-hydroxy-3,4-dihydro-2H-1-benzopyrane (J.Chem. Soc., 3137; 1954) and 1,4-dichlorobutanol according to example 1 (b), or from 1-phenyl-7-hydroxy-3,4-dihydro-2H-1-benzopyrane and 1-chloro-3,4-epoxybutane according to example 1 (c).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US04391821
Source dataset	uspto-grants-1983_07
ORD ID	ord-7f9fa53fa3704fbd8de4029cd2308cd3
Source note	uspto-grants-1983_07