Dimethylformamide dimethyl acetal → HCID 53707584, compound

HRID 1074595Notes

Reaction equation

HRID 1074595 reaction equation
[Cl:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[CH2:4][NH:5][C:6](=[O:10])[CH2:7][C:8]#[N:9].CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>>[Cl:1][C:2]1[CH:14]=[CH:13][CH:12]=[CH:11][C:3]=1[CH2:4][NH:5][C:6](=[O:10])[C:7]([C:8]#[N:9])=[CH:17][N:18]([CH3:19])[CH3:20]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 964628HCID 964628, compound

Product 1

HCID 53707584HCID 53707584, compound

Procedure

As for Example 1, N-o-chlorobenzyl-2-cyanoacetamide, colorless needles, m.p. 108°-109° C., (prepared as described in U.S. Pat. No. 3,116,312) is heated with N,N-dimethylformamide dimethylacetal to give N-o-chlorobenzyl-2-cyano-3-dimethylaminoacrylamide as colorless needles, m.p. 144°-146.5° C.

Sources & evidence

ORD record
ord-4689c073e6f64cfeb4f105905c23a081
Source dataset
uspto-grants-1983_07
Patent number
US04393217

Reaction notes

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