Dimethylformamide dimethyl acetal → HCID 54486704, compound

HRID 1074596Notes

Reaction equation

HRID 1074596 reaction equation
[Br:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[NH:4][C:5](=[O:9])[CH2:6][C:7]#[N:8].CO[CH:16](OC)[N:17]([CH3:19])[CH3:18]>>[Br:1][C:2]1[CH:13]=[CH:12][CH:11]=[CH:10][C:3]=1[NH:4][C:5](=[O:9])[C:6]([C:7]#[N:8])=[CH:16][N:17]([CH3:18])[CH3:19]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 4154641N-(2-bromophenyl)-2-cyanoacetamide

Product 1

HCID 54486704HCID 54486704, compound

Procedure

As for Example 1, 2'-bromo-2-cyanoacetanilide, white crystals, m.p. 140°-141° C. (prepared as described in U.S. Pat. No. 3,116,312), is heated with N,N-dimethylformamide dimethylacetal to give 2'-bromo-2-cyano-3-dimethylaminoacrylanilide as off-white prisms, m.p. 91°-93° C.

Sources & evidence

ORD record
ord-d588ce43605449c09210730da90caa37
Source dataset
uspto-grants-1983_07
Patent number
US04393217

Reaction notes

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