Dimethylformamide dimethyl acetal → HCID 54376494, compound

HRID 1074598Notes

Reaction equation

HRID 1074598 reaction equation
[C:1]([CH2:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][CH3:14])=[O:5])#[N:2].CO[CH:17](OC)[N:18]([CH3:20])[CH3:19]>>[C:1]([C:3](=[CH:17][N:18]([CH3:20])[CH3:19])[C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[CH2:13][CH3:14])=[O:5])#[N:2]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 7318832-cyano-N-(2-ethylphenyl)acetamide

Product 1

HCID 54376494HCID 54376494, compound

Procedure

As for Example 1, 2-cyano-2'-ethylacetanilide as long needles, m.p. 128°-130° C. (prepared by the procedure described in U.S. Pat. No. 3,116,312), is heated with N,N-dimethylformamide dimethylacetal to yield 2-cyano-3-dimethylamino-2'-ethylacrylanilide as colorless prisms, m.p. 102.5°-104° C.

Sources & evidence

ORD record
ord-78c4dd8fb2174334bbfed808b0be2c41
Source dataset
uspto-grants-1983_07
Patent number
US04393217

Reaction notes

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