Dimethylformamide dimethyl acetal → HCID 53973883, compound

HRID 1074603Notes

Reaction equation

HRID 1074603 reaction equation
[C:1]([CH2:3][C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N:13]1[CH:17]=[CH:16][CH:15]=[CH:14]1)=[O:5])#[N:2].CO[CH:20](OC)[N:21]([CH3:23])[CH3:22]>>[C:1]([C:3](=[CH:20][N:21]([CH3:23])[CH3:22])[C:4]([NH:6][C:7]1[CH:12]=[CH:11][CH:10]=[CH:9][C:8]=1[N:13]1[CH:17]=[CH:16][CH:15]=[CH:14]1)=[O:5])#[N:2]

Participants

3

Reactant 2

HCID 78373Dimethylformamide dimethyl acetalHCID 13174849HCID 13174849, compound

Product 1

HCID 53973883HCID 53973883, compound

Procedure

As for Example 1, 2-cyano-2'-(1-pyrrolyl)acetanilide, colorless needles, m.p. 143°-144° C. (prepared by the procedure described in U.S. Pat. No. 3,116,312), is heated with N,N-dimethylformamide dimethylacetal to give 2-cyano-3-dimethylamino-2'-(1-pyrrolyl)acrylanilide as yellow crystals, m.p. 169°-171° C.

Sources & evidence

ORD record
ord-60e378e7d01f43a68ea720a2d7e9a8b6
Source dataset
uspto-grants-1983_07
Patent number
US04393217

Reaction notes

Loading…