Water → HCID 20439642, compound

HRID 1074849Notes

Reaction equation

HRID 1074849 reaction equation
[Cl:1][C:2]1[C:11]([O:12][C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)=[CH:10][CH:9]=[C:8]([N+:20]([O-:22])=[O:21])[C:3]=1[NH:4][CH2:5][CH2:6]O.P(Cl)(Cl)(Cl)(Cl)[Cl:24].O.C(=O)(O)[O-].[Na+]>C1(C)C=CC=CC=1>[Cl:1][C:2]1[C:11]([O:12][C:13]2[CH:18]=[CH:17][C:16]([Cl:19])=[CH:15][CH:14]=2)=[CH:10][CH:9]=[C:8]([N+:20]([O-:22])=[O:21])[C:3]=1[NH:4][CH2:5][CH2:6][Cl:24]

Participants

6

Reactant 4

HCID 962WaterHCID 24819Phosphorus pentachlorideHCID 516892Sodium BicarbonateHCID 20439640HCID 20439640, compound

Product 1

HCID 20439642HCID 20439642, compoundYield 75.9%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

An amount of 4.5 gm of 2-chloro-3-(4-chlorophenoxy)-6-nitro-N-2-hydroxyethylaniline was dissolved in 40 ml of toluene and mixed with 2.9 gm of PCl5, spontaneous heating and gas generation taking place. After 30 minutes the mixture was shaken with water and sodium bicarbonate solution and is evaporated. 3.6 gm of a yellowy brown oil were obtained (76% of theory).

Workup

  1. temperaturespontaneous heating
  2. customis evaporated

Sources & evidence

ORD record
ord-da304e33358c4c11ac75f673559bacd9
Source dataset
uspto-grants-1983_07
Patent number
US04394159

Reaction notes

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