Acetic Acid → HCID 9795017, compound

HRID 1074976Notes

Reaction equation

HRID 1074976 reaction equation
C([C:3]1[CH:4]=[CH:5][C:6]2[CH:12]=[CH:11][C:10]3[CH:13]=[CH:14]C=[CH:16][C:9]=3[S:8][C:7]=2[CH:17]=1)#N.Cl.[C:19]([OH:22])(=[O:21])[CH3:20]>O>[CH:13]1[C:10]2[CH:11]=[CH:12][C:6]3[CH:5]=[CH:4][CH:3]=[CH:17][C:7]=3[S:8][C:9]=2[CH:16]=[C:20]([C:19]([OH:22])=[O:21])[CH:14]=1

Participants

5

Reactant 3

HCID 176Acetic AcidHCID 313Hydrochloric AcidHCID 13490383HCID 13490383, compound

Product 1

HCID 9795017HCID 9795017, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

2.0 G. 3-cyanodibenzo[b,f]thiepin are refluxed in a mixture of 25 cc. concentrated HCl and 25 cc. glacial acetic acid for 19 hours; the acid separates from the hot solution. After cooling, the mixture is diluted with water and the light yellow solid is filtered and washed well with water. The yield of dibenzo[b,f]thiepin-3-carboxylic acid is 2.07 g. (95.8%), m.p. 251° C.-254° C.

Workup

  1. temperatureAfter cooling
  2. filtrationthe light yellow solid is filtered
  3. washwashed well with water

Sources & evidence

ORD record
ord-a3413d544e2741e3890d0f00c5832170
Source dataset
uspto-grants-1983_07
Patent number
US04394515

Reaction notes

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