Diazomethane → Methyl-10,11-dihydro-11-hydroxydibenzo[b,f]thiepin-3-carboxylate
Reaction equation
[OH:1][CH:2]1[CH2:8][C:7]2[CH:9]=[CH:10][CH:11]=[CH:12][C:6]=2[S:5][C:4]2[CH:13]=[C:14]([C:17]([OH:19])=[O:18])[CH:15]=[CH:16][C:3]1=2.[N+](=[CH2:22])=[N-]>CCOCC>[CH3:22][O:18][C:17]([C:14]1[CH:15]=[CH:16][C:3]2[CH:2]([OH:1])[CH2:8][C:7]3[CH:9]=[CH:10][CH:11]=[CH:12][C:6]=3[S:5][C:4]=2[CH:13]=1)=[O:19]Participants
4
Reactant 2
Product 1
Reagents, catalysts & solvents 1
Procedure
13.5 G. 10,11-dihydro-11-hydroxydibenzo[b,f]thiepin-3-carboxylic acid is suspended in ether and excess diazomethane is added in portions. A clear solution results which is filtered from small particles in suspension and the filtrate evaporated to dryness to a yellow oil weighing 14.2 g.
Workup
- customA clear solution results which
- filtrationis filtered from small particles in suspension
- customthe filtrate evaporated to dryness to a yellow oil
Sources & evidence
- ORD record
- ord-9ba9227263fd4e38b09073962c45ec9f
- Source dataset
- uspto-grants-1983_07
- Patent number
- US04394515
Reaction notes
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