Hydrochloric Acid → HCID 13151855, compound

Participants

Reaction Steps

780 Mg. 3-cyano-10,11-dihydro-11-oxodibenzo[b,f]thiepin 5-oxide is refluxed for four hours in a mixture of 50 cc. 10% aqueous sodium hydroxide and 50 cc. ethanol. The reaction mixture is diluted with water, acidified with hydrochloric acid, filtered and dried under vacuum in the oven at 70° C. The solid is recrystallized from a mixture of dimethylformamide and methanol to yield 360 mg. of the pure acid, m.p. 273° C. dec.

Provenance & Evidence