HuagongsheHuagongshe Chemistry Print Report · For research reference only
m-Chloroperbenzoic acid → 8-Chloro-3-cyanodibenzo[b,f]thiepin-5,5-dioxide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | m-Chloroperbenzoic acid | HCID 70297 | — |
| Reactant | Calcium Hydroxide | HCID 6093208 | — |
| Reactant | 8-Chloro-3-cyanodibenzo[b,f]thiepin | HCID 13151889 | — |
| Solvent | Chloroform | HCID 6212 | — |
| Product | 8-Chloro-3-cyanodibenzo[b,f]thiepin-5,5-dioxide | HCID 13151890 | — |
Reaction Steps
400 Mg. 8-chloro-3-cyanodibenzo[b,f]thiepin is dissolved in 30 cc. chloroform and 2 g. m-chloroperbenzoic acid added, and the solution stirred for 24 hours. 5 G. calcium hydroxide is added, the mixture stirred for five minutes and filtered through celite. The organic filtrate is evaporated to dryness and the residue chromatographed on silica gel and eluted with 5% ethyl acetate/benzene mixture to yield 339 mg. (76%) pure sulfone, m.p. 228°-230° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04394515 |
| Source dataset | uspto-grants-1983_07 |
| ORD ID | ord-60b89d9ebb8e4f199da891dadebcf87d |
| Source note | uspto-grants-1983_07 |