Methylamine → HCID 178482371, compound

HRID 1075087Notes

Reaction equation

HRID 1075087 reaction equation
CO[C:3]1C(OC)=NS(=O)(=O)[N:4]=1.[NH:12]([C:16]1[O:17][CH:18]=[C:19]([CH2:21][CH2:22][CH2:23][CH2:24][NH:25][C:26]2(OC)[NH:30][S:29](=[O:32])(=[O:31])[N:28]=[CH:27]2)[N:20]=1)[C:13]([NH2:15])=[NH:14].CN>>[NH:12]([C:16]1[O:17][CH:18]=[C:19]([CH2:21][CH2:22][CH2:23][CH2:24][NH:25][C:26]2([NH:4][CH3:3])[NH:30][S:29](=[O:32])(=[O:31])[N:28]=[CH:27]2)[N:20]=1)[C:13]([NH2:15])=[NH:14]

Participants

4

Reactant 3

HCID 6329MethylamineHCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxideHCID 178494170HCID 178494170, compound

Product 1

HCID 178482371HCID 178482371, compound

Procedure

When a suspension of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide is reacted with an equimolar amount of 4-[(2-quanidino-4-oxazolyl]butylamine [prepared according to the procedure described in Belgian Pat. No. 866,155] and the resultant 3-{4-[(2-guanidino-4-oxazolyl]butylamino}-4-methoxy-1,2,5-thiadiazole 1,1-dioxide is treated with excess methylamine, the title compound is thereby produced.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-c25f85d7b8044c2985ca93da0613cf14
Source dataset
uspto-grants-1983_07
Patent number
US04394508

Reaction notes

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