Methylamine → HCID 178482526, compound

HRID 1075116Notes

Reaction equation

HRID 1075116 reaction equation
CO[C:3]1[C:7](OC)=[N:6][S:5](=[O:11])(=[O:10])[N:4]=1.[NH:12]([C:16]1[O:20][N:19]=[C:18]([CH2:21][S:22][CH2:23][CH2:24][NH2:25])[N:17]=1)[C:13]([NH2:15])=[NH:14].[CH3:26][NH2:27]>>[NH:12]([C:16]1[O:20][N:19]=[C:18]([CH2:21][S:22][CH2:23][CH2:24][NH:25][C:7]2[C:3]([NH:27][CH3:26])=[N:4][S:5](=[O:10])(=[O:11])[N:6]=2)[N:17]=1)[C:13]([NH2:15])=[NH:14]

Participants

4

Reactant 3

HCID 6329MethylamineHCID 122305383,4-Dimethoxy-1,2,5-thiadiazole 1,1-dioxideHCID 178512728HCID 178512728, compound

Product 1

HCID 178482526HCID 178482526, compound

Procedure

When a methanolic solution of 3,4-dimethoxy-1,2,5-thiadiazole 1,1-dioxide is successively treated with an equimolar amount of 2-[(5-guanidino-1,2,4-oxadiazol-3-yl)methylthio]ethylamine [prepared according to the procedure described in published European Patent Application 6286] and excess methylamine, the title compound is thereby produced.

Workup

  1. customprepared

Sources & evidence

ORD record
ord-58be9debde974e4bbc47db7d066b0cf1
Source dataset
uspto-grants-1983_07
Patent number
US04394508

Reaction notes

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