HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Iodopropane → 1-Propyl-5-fluoropyrimid-2-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Iodopropane | HCID 33643 | — |
| Reactant | 5-Fluoropyrimidin-2-one | HCID 101498 | — |
| Reactant | Potassium | HCID 5462222 | — |
| Product | 1-Propyl-5-fluoropyrimid-2-one | HCID 20494300 | 20% |
Reaction Steps
1-Propyl-5-fluoropyrimid-2-one was prepared as above from the potassium salt of 5-fluoropyrimid-2-one and n-propyl iodide in 20% yield after 48 hours; m.p. =93° C. (ligroin). (Found: C, 54.04; H, 5.82; Calc for C7H9FN2O: C, 53.86; H, 5.81).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US04395406 |
| Source dataset | uspto-grants-1983_07 |
| ORD ID | ord-538f11a3971643afb232101c5644a40d |
| Source note | uspto-grants-1983_07 |