Methyl iodide → HCID 20494304, compound

Participants

Reaction Steps

1-(2-Dimethylaminoethyl)-5-chloropyrimid-2-one (0.004 mol) and methyl iodide (0.006 mol) were dissolved in acetonitrile (20 ml) and the reaction mixture was stirred at room temperature for 6 h. The precipitate was then collected, washed with ether and recrystallized by dissolving in boiling isopropanol (50 ml) to which water (in all 14 ml) was added dropwise, until dissolution was complete; yield 50%, m.p. 235° C. (decomp.). (Found: C, 31.34; H, 4.48. Calc. for C9H15ClIN3O: C, 31.46; H, 4.40).

Provenance & Evidence