Ethyl Acetate → HCID 20494297, compound

HRID 1075156Notes

Reaction equation

[F:1][C:2]1[CH:3]=[N:4][C:5](=[O:8])[NH:6][CH:7]=1.[C:9]([O:12][CH2:13][CH3:14])(=[O:11])[CH3:10]>>[CH2:13]([O:12][C:9]([CH2:10][N:4]1[CH:3]=[C:2]([F:1])[CH:7]=[N:6][C:5]1=[O:8])=[O:11])[CH3:14]

Participants

Reactant 2

HCID 8857Ethyl Acetate

HCID 1014985-Fluoropyrimidin-2-one

Product 1

HCID 20494297HCID 20494297, compoundYield 31%

Procedure

Prepared as above from 5-fluoropyrimid-2-one in 31% yield, m.p. 121° (ethyl acetate). (Found: C, 47.90; H, 4.70. Calc. for C8H9FN2O3 : C, 48.02; H, 4.53).

Sources & evidence

ORD record: ord-0adda978349c441d8d44ae9065f00a3a
Source dataset: uspto-grants-1983_07
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US04395406

Reaction notes

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