反应详情

A mixture of the potassium salt of 5-bromopyrimid-2-one (0.01 mol) and 4-bromo-1-butene (0.015 mol) was heated in methanol (60 ml) at 70° C. for 40 h. The reaction mixture was then evaporated and the mixture extracted with chloroform. This solution was washed with 1 N NaOH (5 ml). with water (5 ml) and dried (MgSO4) before evaporating; yield 50%, m.p. 127°-128° C. (acetone). (Found: C, 42.06; H, 3.94. Calc. for C8H9BrN2O: C, 41.94; H, 3.96).

1. customThe reaction mixture was then evaporated
2. extractionthe mixture extracted with chloroform
3. washThis solution was washed with 1 N NaOH (5 ml)
4. dry with materialwith water (5 ml) and dried (MgSO4)
5. custombefore evaporating