反应详情

温度

65 °C

A 500 mL, 3-necked, round-bottomed flask equipped with air condensers and a magnetic stirring plate was charged with N,N-dimethylhexylamine (199.46 grams, 1.54 moles), 1-bromo-3-chloropropane (243.00 grams, 1.54 moles) and 250 mL of methanol The reaction was maintained at 65° C. for 24 hours. Solvent was removed by rotary evaporation under reduced pressure to yield a brown, viscous oil. Yield 445.8 grams (1.55 moles, 100%).

1. customA 500 mL, 3-necked, round-bottomed flask equipped with air condensers
2. customSolvent was removed by rotary evaporation under reduced pressure
3. customto yield a brown, viscous oil