Aspirin → 2-Hydroxy-N-[4-(1-methylethyl)phenyl]benzamide

HRID 1075585Notes

Reaction equation

C([O:4][C:5]1[C:6](=[CH:10][CH:11]=[CH:12][CH:13]=1)[C:7]([OH:9])=O)(=O)C.[CH:14]([C:17]1[CH:23]=[CH:22][C:20]([NH2:21])=[CH:19][CH:18]=1)([CH3:16])[CH3:15]>>[CH:14]([C:17]1[CH:23]=[CH:22][C:20]([NH:21][C:7](=[O:9])[C:6]2[CH:10]=[CH:11][CH:12]=[CH:13][C:5]=2[OH:4])=[CH:19][CH:18]=1)([CH3:16])[CH3:15]

Participants

Reactant 2

HCID 2244Aspirin

HCID 74644-Isopropylaniline

Product 1

HCID 97950432-Hydroxy-N-[4-(1-methylethyl)phenyl]benzamide

Procedure

This compound was obtained as a white solid starting from acetylsalicyclic acid and 4isopropylaniline using the same procedure described in example 5.

Workup

customThis compound was obtained as a white solid

Sources & evidence

ORD record: ord-37854571b5c149f1b8e0a3ad337e2300
Source dataset: uspto-grants-1999_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05905090

Reaction notes

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