Sodium Hydroxide → HCID 131721271, compound

Participants

Reaction Steps

To a solution of 2-[5-(2-oxindol-3-ylidenemethyl)quinol-8-yloxy] acetic acid ethyl ester (150 mg, 0.40 mmol) in dioxane (20 ml) was added 2N sodium hydroxide (2 ml) and the mixture was stirred for 1 h at room temperature. The resulting crystals were separated by filtration, washed with dioxane and dried. Thus pure title compound was obtained in 81.5% yield (120 mg).

Provenance & Evidence