Dimethylamine → HCID 21540598, compound

Participants

Reaction Conditions

Reaction Steps

A glass reaction tube was charged with 5.0g. (0.016 mole) of 6-chloro-1-ethyl-2-methyl-7-nitro-5-trifluoromethylbenzimidazole, 20 ml. of dimethoxyethane and 15 ml. of dimethylamine and then sealed. The sealed tube was maintained at 125°C. for 16 days and then opened. The contents were evaporated to dryness and the residue extracted with hot hexane, from which crystallized 3.1g. of the desired product m.p. 111°-115°C. after recrystallization from hexane.

Provenance & Evidence