反应详情

Methyl 2-amino-5-chloropyrazine-3-carboxylate was treated as described in Example 1 with 25 ml. of pyrrolidine in 100 ml. of methanol. Crystallization from ether yielded 7 g. (72%) of the above-named product with m.p. 90°-95°. Recrystallization from 2-propanol gave pale yellow needles with m.p. 95°-97°.

1. customCrystallization from ether
2. customyielded 7 g
3. customRecrystallization from 2-propanol
4. customgave pale yellow needles with m.p. 95°-97°