反应详情

温度

25 °C

In 400 parts by volume of ethyl formate is dissolved 35 parts of β-aminopropionitrile. To the solution is added 100 parts of a methanol solution which includes 32 parts of sodium methylate. The mixture is put into an autoclave with a capacity of 1,000 parts by volume. Into the mixture is introduced carbon monoxide at 50 kg/cm2G at 70°C for 3 hours. After the reaction, the mixture is cooled at 25°C. The solvent is removed and the crystals are recovered by filtration and dried, whereby 77 parts of α-sodioformyl-β-formylaminopropionitrile is obtained as crude crystals. Purity; 90 %. Yield: 94 %. Melting point; 190°C.

1. customAfter the reaction
2. customThe solvent is removed
3. filtrationthe crystals are recovered by filtration
4. customdried